Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146668 | 0.71 | LMNA (0.45) | ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL149941 | 0.71 | POLB (0.53) | ALDH1A1KDM4EHPGDLMNAGLA | |
| SCHEMBL30434999 | 0.69 | KDM4E (0.51) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL144883 | 0.69 | KDM4E (0.51) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL30884721 | 0.68 | TLR8 (0.46) | ALDH1A1KDM4EHPGDTLR8NPC1 | |
| SCHEMBL4716253 | 0.68 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL12113956 | 0.67 | POLB (0.44) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL31569481 | 0.67 | POLB (0.44) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL456396 | 0.66 | TLR8 (0.57) | ALDH1A1KDM4EHPGDTLR8NPC1 | |
| SCHEMBL151590 | 0.66 | ALDH1A1 (0.59) | ALDH1A1KDM4ENPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107252429-A | New antiinflammatory | 雷斯韦洛吉克斯公司 | 2017-10-17 | — | — | CN | disclosed |
| CN-102458405-B | Novel anti-inflammatory agents | 雷斯韦洛吉克斯公司 | 2017-06-23 | — | — | CN | disclosed |