Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909470 | 0.85 | LMNA (0.53) | LMNANUDT1ADORA2AKDM4EPKM | |
| SCHEMBL971895 | 0.82 | LMNA (0.62) | LMNANUDT1ADORA2AKDM4EPKM | |
| SCHEMBL28239158 | 0.80 | LMNA (0.61) | LMNANUDT1ADORA2AKDM4EPKM | |
| SCHEMBL27810976 | 0.80 | LMNA (0.61) | LMNANUDT1ADORA2AKDM4EPKM | |
| SCHEMBL29897809 | 0.76 | MAPK1 (0.48) | LMNAKDM4ETDP1L3MBTL1ESR1 | |
| SCHEMBL1766036 | 0.76 | L3MBTL1 (0.62) | LMNANUDT1ADORA2AKDM4EPKM | |
| SCHEMBL22470183 | 0.76 | L3MBTL1 (0.62) | LMNANUDT1ADORA2AKDM4EPKM | |
| SCHEMBL13614893 | 0.74 | L3MBTL1 (0.60) | LMNANUDT1ADORA2AKDM4EPKM | |
| SCHEMBL28962062 | 0.74 | NUDT1 (0.58) | LMNANUDT1ADORA2AKDM4EPKM | |
| SCHEMBL2512737 | 0.74 | KDM4E (0.56) | LMNAKDM4ETDP1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106892908-A | A kind of synthetic method of 5- (the bromo- 2,3- diphenylquinoxalines -5-yl of 8-) thiophene -2-formaldehyde | 西安瑞联新材料股份有限公司 | 2017-06-27 | — | — | CN | disclosed |