Benzene

Benzene

SCHEMBL28159019

CC(C)(C)c1ccc(O)c(C(C)(C)C)c1.CCC(C)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.c1ccccc1

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.52
CYP1A2 P05177 2/20 0.52
CYP3A4 P08684 1/20 0.52
TSHR P16473 1/20 0.52
CYP2C19 P33261 1/20 0.52
RORC P51449 1/20 0.46
ALDH1A1 P00352 4/20 0.40
GAA P10253 4/20 0.40
ALOX15 P16050 3/20 0.40
HSD17B10 Q99714 3/20 0.40
HPGD P15428 2/20 0.40
PKM P14618 2/20 0.40
USP2 O75604 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
NR1I2 O75469 1/20 0.39
LMNA P02545 1/20 0.39
MIF P14174 1/20 0.39
TYR P14679 1/20 0.39
HTT P42858 1/20 0.39
NFE2L2 Q16236 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5829731 0.82 RORC (0.54) CYP2C9CYP1A2CYP3A4TSHRCYP2C19
SCHEMBL144821 0.82 CA2 (0.50) CYP2C9CYP1A2CYP3A4TSHRCYP2C19
SCHEMBL875855 0.81 ALDH1A1 (0.59) CYP2C9CYP1A2CYP3A4TSHRCYP2C19
SCHEMBL11761908 0.81 TSHR (0.60) CYP2C9CYP1A2CYP3A4TSHRCYP2C19
SCHEMBL8170388 0.79 ALDH1A1 (0.57) CYP2C9CYP1A2CYP3A4TSHRCYP2C19
Benzene SCHEMBL28155736 0.79 ALDH1A1 (0.61) CYP2C9CYP1A2CYP3A4TSHRCYP2C19
SCHEMBL2951999 0.78 CYP1A2 (0.44) CYP2C9CYP1A2CYP3A4TSHRCYP2C19
SCHEMBL5054631 0.77 HSPA5 (0.54) CYP2C9CYP1A2CYP3A4TSHRCYP2C19
Propofol SCHEMBL4048377 0.76 TSHR (0.50) CYP2C9CYP1A2CYP3A4TSHRCYP2C19
SCHEMBL8986507 0.75 ALDH1A1 (0.61) CYP2C9CYP1A2TSHRALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106905711-A Styrene-butadiene-copolymer of non-carboxylation and its production and use 巴斯夫欧洲公司 2017-06-30 CN disclosed