Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ACP1 | P24666 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27956587 | 0.81 | KDM4E (0.51) | MEN1KMT2AKDM4ECYP3A4MAPT | |
| SCHEMBL28811710 | 0.80 | MEN1 (0.46) | MEN1KMT2AKDM4ECYP3A4MAPT | |
| SCHEMBL28159093 | 0.77 | ANO1 (0.46) | KDM4EHSD17B10ANO1HPGDLMNA | |
| SCHEMBL8636723 | 0.76 | MEN1 (0.56) | MEN1KMT2AKDM4ECYP3A4MAPT | |
| SCHEMBL28159090 | 0.75 | ABCB1 (0.39) | MEN1KMT2APTPN1ACP1ABCB1 | |
| SCHEMBL1918164 | 0.74 | RAB9A (0.60) | MEN1KMT2AKDM4ECYP3A4MAPT | |
| SCHEMBL8635613 | 0.74 | MEN1 (0.54) | MEN1KMT2AKDM4ECYP3A4MAPT | |
| SCHEMBL120304 | 0.73 | RAB9A (0.56) | MEN1KMT2AKDM4ECYP3A4MAPT | |
| SCHEMBL23218151 | 0.71 | GABRP (0.51) | KMT2AKDM4EANO1LMNASMN1; SMN2 | |
| SCHEMBL29592241 | 0.71 | GABRP (0.51) | KMT2AKDM4EANO1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567442-A | Inhibitors of hepatitis C virus polymerase | 共晶制药公司 | 2018-01-09 | — | — | CN | disclosed |
| CN-106986862-A | Hepatitis c inhibitor and application thereof | ABBVIE 公司 | 2017-07-28 | — | — | CN | disclosed |