Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 2/20 | 0.43 |
| ▸ | EDNRA | P25101 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28246631 | 0.80 | EDNRB (0.44) | EDNRBEDNRAALDH1A1POLBHPGD | |
| SCHEMBL6095770 | 0.79 | MEN1 (0.43) | EDNRBEDNRAALDH1A1POLBHPGD | |
| SCHEMBL28559637 | 0.79 | ALDH1A1 (0.41) | EDNRBEDNRAALDH1A1POLBHPGD | |
| SCHEMBL30825174 | 0.79 | MEN1 (0.43) | EDNRBEDNRAALDH1A1POLBHPGD | |
| SCHEMBL29241693 | 0.75 | ALDH1A1 (0.38) | EDNRBEDNRAALDH1A1POLBHPGD | |
| SCHEMBL28283575 | 0.73 | GAA (0.58) | ALDH1A1POLBMEN1KMT2AGAA | |
| SCHEMBL21598442 | 0.72 | ALDH1A1 (0.38) | EDNRBEDNRAALDH1A1POLBHPGD | |
| SCHEMBL30681424 | 0.71 | MEN1 (0.39) | ALDH1A1POLBHPGDMEN1KMT2A | |
| SCHEMBL19410707 | 0.70 | ALDH1A1 (0.43) | ALDH1A1POLBHPGDMEN1KMT2A | |
| SCHEMBL28029965 | 0.68 | MEN1 (0.45) | ALDH1A1POLBMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108698997-A | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-108349949-A | N- substituted indole derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-104910148-B | Aminotriazole(ATA) and pyridine and its as kinase inhibitor purposes | 西格诺药品有限公司 | 2017-06-27 | — | — | CN | disclosed |