Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3024397 | 0.98 | MAPT (0.53) | MAPTLMNAADRA2AADRA2BADRA2C | |
| SCHEMBL116229 | 0.98 | MAPT (0.53) | MAPTLMNAADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL8872527 | 0.96 | ADRA2A (0.54) | MAPTLMNAADRA2AADRA2BADRA2C | |
| Acetone SCHEMBL28243789 | 0.89 | CYP1A2 (0.57) | MAPTLMNAADRA2AADRA2BADRA2C | |
| Phosphoric Acid SCHEMBL8529442 | 0.89 | ADRA2A (0.50) | MAPTLMNAADRA2AADRA2BADRA2C | |
| Phosphoric Acid SCHEMBL9079479 | 0.86 | ADRA2A (0.47) | MAPTLMNAADRA2AADRA2BADRA2C | |
| Cadaverine Tartrate SCHEMBL28598769 | 0.83 | ADRA2A (0.45) | MAPTLMNAADRA2AADRA2BADRA2C | |
| Cadaverine Tartrate SCHEMBL28586029 | 0.83 | ADRA2A (0.45) | MAPTLMNAADRA2AADRA2BADRA2C | |
| SCHEMBL19461607 | 0.82 | MAPT (0.71) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL25336501 | 0.82 | IDO1 (0.42) | MAPTLMNAADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026044-A | Pyridines and their use in cancer therapy | E·S·J·阿内尔 | 2018-05-11 | — | — | CN | disclosed |
| CN-104910148-B | Aminotriazole(ATA) and pyridine and its as kinase inhibitor purposes | 西格诺药品有限公司 | 2017-06-27 | — | — | CN | disclosed |