Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL9079479 | 0.93 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CSLC2A1MAPT | |
| SCHEMBL116229 | 0.91 | MAPT (0.53) | ADRA2AADRA2BADRA2CSLC2A1MAPT | |
| SCHEMBL3024397 | 0.91 | MAPT (0.53) | ADRA2AADRA2BADRA2CSLC2A1MAPT | |
| Methane SCHEMBL28159882 | 0.89 | MAPT (0.52) | ADRA2AADRA2BADRA2CSLC2A1MAPT | |
| Hydrochloric Acid SCHEMBL8872527 | 0.89 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CSLC2A1MAPT | |
| Acetone SCHEMBL28243789 | 0.86 | CYP1A2 (0.57) | ADRA2AADRA2BADRA2CSLC2A1MAPT | |
| Cadaverine Tartrate SCHEMBL28586029 | 0.80 | ADRA2A (0.45) | ADRA2AADRA2BADRA2CSLC2A1MAPT | |
| Cadaverine Tartrate SCHEMBL28598769 | 0.80 | ADRA2A (0.45) | ADRA2AADRA2BADRA2CSLC2A1MAPT | |
| Carbromal SCHEMBL9170995 | 0.78 | CYP2C19 (0.42) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| SCHEMBL19461607 | 0.76 | MAPT (0.71) | MAPTLMNAGAACYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570250-B1 | Crystalline structure of monohydrogentartrates, process for its preparation and application thereof | FRANCE TELECOM (FR) | 1998-06-03 | — | — | EP | disclosed |
| EP-0619308-B1 | Crystalline structures of halides of 2-amino-5-nitro-pyridinium, process for their preparation and an electrooptical device with such structures | FRANCE TELECOM (FR) | 1998-03-11 | — | — | EP | disclosed |
| US-5637717-A | 2-amino-5-nitropyridinium halide crystal structure and process for the preparation of said crystal structures | FRANCE TELECOM (FR) | 1997-06-10 | — | — | US | disclosed |
| US-5374734-A | Monohydrogentartrate crystalline structure having nonlinear quadratic effects | FRANCE TELECOM (FR) | 1994-12-20 | — | — | US | disclosed |
| EP-0619308-A1 | Crystalline structures of the hydrogen chloride salt of 2-amino-5-nitro-pyridinium, process for their preparation and an electrooptical device with such structures | FRANCE TELECOM (FR) | 1994-10-12 | — | — | EP | disclosed |
| EP-0570250-A2 | Crystalline structure of monohydrogentartrates, process for its preparation and application thereof | FRANCE TELECOM (FR) | 1993-11-18 | — | — | EP | disclosed |
| EP-0488869-A1 | Salts of 2-amino-5-nitropyridinium for non-linear and electro-optic use, and a process for their preparation | FRANCE TELECOM (FR) | 1992-06-03 | — | — | EP | disclosed |