Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91107 | 0.83 | ALDH1A1 (0.50) | DRD2HTR2AHRH1MAPTALDH1A1 | |
| SCHEMBL1991688 | 0.81 | MAPT (0.50) | DRD2HTR2AHRH1MAPTALDH1A1 | |
| SCHEMBL21815733 | 0.81 | KDM4E (0.45) | DRD2HTR2AHRH1MAPTALDH1A1 | |
| SCHEMBL188731 | 0.78 | KDM4E (0.61) | MAPTALDH1A1KDM4EPKMHRH3 | |
| SCHEMBL1126955 | 0.76 | MAPT (0.57) | MAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL1814737 | 0.74 | DRD2 (0.47) | DRD2HTR2AHRH1KMT2AMEN1 | |
| SCHEMBL5795262 | 0.73 | — | — | |
| SCHEMBL20548927 | 0.73 | DRD2 (0.40) | DRD2HTR2AHRH1MAPTALDH1A1 | |
| SCHEMBL28474231 | 0.71 | MAPT (0.41) | DRD2MAPTALDH1A1KDM4EPKM | |
| SCHEMBL26922761 | 0.70 | KCNH2 (0.45) | DRD2HTR2AHRH1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928198-A | Sulfamide derivative and preparation method and application | 成都先导药物开发有限公司 | 2017-07-07 | — | — | CN | disclosed |