SCHEMBL28160484

SCHEMBL28160484

CCc1ccnn1[C@@H](C)CN

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.36
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28160485 1.00 L3MBTL1 (0.36) L3MBTL1ALDH1A1
SCHEMBL25858729 0.85 L3MBTL1 (0.47) L3MBTL1ALDH1A1
SCHEMBL10271243 0.80 ALDH1A1 (0.36) L3MBTL1ALDH1A1
SCHEMBL24768136 0.75 L3MBTL1 (0.32) L3MBTL1ALDH1A1
SCHEMBL24768124 0.73 ALDH1A1 (0.35) L3MBTL1ALDH1A1
SCHEMBL26140171 0.71 ALDH1A1 (0.45) L3MBTL1ALDH1A1
SCHEMBL24963265 0.71 ALDH1A1 (0.35) L3MBTL1ALDH1A1
Hydrochloric Acid SCHEMBL17699019 0.67 ALDH1A1 (0.40) L3MBTL1ALDH1A1
SCHEMBL9946497 0.67
SCHEMBL3855797 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107018661-A The purposes of 6,7 dihydro-pyrazolos [1,5 a] pyrazine 4 (5H) assimilation compound and its negative sense allosteric modulators as MGLUR2 acceptors 詹森药业有限公司 2017-08-04 CN disclosed