Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28160484 | 0.85 | L3MBTL1 (0.36) | L3MBTL1ALDH1A1 | |
| SCHEMBL28160485 | 0.85 | L3MBTL1 (0.36) | L3MBTL1ALDH1A1 | |
| SCHEMBL10271243 | 0.83 | ALDH1A1 (0.36) | L3MBTL1ALDH1A1 | |
| SCHEMBL2931061 | 0.78 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1MEN1CYP1A2CYP2C19 | |
| SCHEMBL24768136 | 0.78 | L3MBTL1 (0.32) | L3MBTL1ALDH1A1 | |
| SCHEMBL26050934 | 0.76 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1MEN1CYP1A2CYP2C19 | |
| SCHEMBL21133940 | 0.76 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1MEN1CYP1A2CYP2C19 | |
| SCHEMBL28038000 | 0.76 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1MEN1CYP1A2CYP2C19 | |
| SCHEMBL24768124 | 0.76 | ALDH1A1 (0.35) | L3MBTL1ALDH1A1 | |
| SCHEMBL26140171 | 0.74 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210850-A1 | PROCESS FOR PREPARING SUBSTITUTED PYRAZOLO[1,5-a]PYRAZINES | Sumitomo Pharma Co., Ltd. (JP) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210850-A1 | PROCESS FOR PREPARING SUBSTITUTED PYRAZOLO[1,5-a]PYRAZINES | CYP3A5, CYP2F1, CYP4Z1 | L3MBTL1 4858/4885ALDH1A1 232/4885MEN1 1221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.