Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | THRA | P10827 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.49 |
| ▸ | RARB | P10826 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16050407 | 0.98 | ALDH1A1 (0.70) | GPR84ALDH1A1HPGDHSD17B10THRA | |
| SCHEMBL22040784 | 0.98 | ALDH1A1 (0.70) | GPR84ALDH1A1HPGDHSD17B10THRA | |
| SCHEMBL28049655 | 0.98 | GPR84 (0.70) | GPR84ALDH1A1HPGDHSD17B10THRA | |
| SCHEMBL16050416 | 0.96 | GPR84 (0.72) | GPR84ALDH1A1HPGDHSD17B10THRA | |
| SCHEMBL290207 | 0.89 | PTGS2 (0.67) | GPR84ALDH1A1HPGDHSD17B10THRA | |
| SCHEMBL16050465 | 0.88 | GPR84 (0.62) | GPR84ALDH1A1HPGDHSD17B10THRA | |
| SCHEMBL15199282 | 0.84 | ALDH1A1 (0.67) | GPR84ALDH1A1HPGDHSD17B10PPARA | |
| SCHEMBL28899619 | 0.84 | ALDH1A1 (0.67) | GPR84ALDH1A1HPGDHSD17B10PPARA | |
| Setogepram SCHEMBL19095287 | 0.84 | ALDH1A1 (0.67) | GPR84ALDH1A1HPGDHSD17B10PPARA | |
| SCHEMBL17678364 | 0.84 | GPR84 (0.71) | GPR84ALDH1A1HPGDHSD17B10PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106999458-B | Substituted aromatic compounds and pharmaceutical compositions for the prevention and treatment of diabetes | 普罗米蒂克医药SMT有限公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-106999458-A | Substituted aromatic compounds and pharmaceutical compositions for the prevention and treatment of diabetes | 普罗米蒂克医药SMT有限公司 | 2017-08-01 | — | — | CN | disclosed |