Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL282886 | 0.97 | MEN1 (0.44) | MAPTMEN1RAB9AKMT2ANPSR1 | |
| SCHEMBL4898659 | 0.94 | KDM4E (0.41) | MAPTMEN1RAB9AKMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL287358 | 0.92 | KDM4E (0.40) | MAPTMEN1RAB9AKMT2ANPSR1 | |
| SCHEMBL284087 | 0.87 | CNR2 (0.40) | KDM4EMAPK14CNR2CNR1 | |
| SCHEMBL24007963 | 0.83 | KDM4E (0.38) | MEN1KMT2AKDM4EMAPK14GRN | |
| SCHEMBL15925334 | 0.83 | CRHR1 (0.40) | MAPTMEN1RAB9AKMT2ANPSR1 | |
| SCHEMBL2816044 | 0.81 | PIK3CA (0.40) | MAPTNPSR1KDM4EMAPK14CNR2 | |
| SCHEMBL25745878 | 0.79 | CNR2 (0.47) | MAPTMEN1RAB9AKMT2ANPSR1 | |
| SCHEMBL27800919 | 0.79 | P2RY14 (0.34) | MAPTMEN1RAB9AKMT2ANPSR1 | |
| SCHEMBL12789844 | 0.79 | P2RY14 (0.36) | MAPTMEN1RAB9AKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3212241-B1 | RADIOLABELED CANNABINOID RECEPTOR 2 LIGAND | HOFFMANN LA ROCHE (CH) | 2019-05-08 | — | — | EP | disclosed |
| US-10227308-B2 | Radiolabeled cannabinoid receptor 2 ligand | HOFFMANN-LA ROCHE INC. (US) | 2019-03-12 | — | — | US | disclosed |
| US-10227308-B2 | Radiolabeled cannabinoid receptor 2 ligand | HOFFMANN-LA ROCHE INC. (US) | 2019-03-12 | — | — | US | disclosed |
| EP-3212241-A1 | RADIOLABELED CANNABINOID RECEPTOR 2 LIGAND | F. Hoffmann-La Roche AG (CH) | 2017-09-06 | — | — | EP | disclosed |
| US-20170166534-A1 | RADIOLABELED CANNABINOID RECEPTOR 2 LIGAND | HOFFMANN-LA ROCHE INC. (US) | 2017-06-15 | — | — | US | disclosed |
| US-20170166534-A1 | RADIOLABELED CANNABINOID RECEPTOR 2 LIGAND | HOFFMANN-LA ROCHE INC. (US) | 2017-06-15 | — | — | US | disclosed |
| US-20170166534-A1 | RADIOLABELED CANNABINOID RECEPTOR 2 LIGAND | HOFFMANN-LA ROCHE INC. (US) | 2017-06-15 | — | — | US | disclosed |
| WO-2016066534-A1 | RADIOLABELED CANNABINOID RECEPTOR 2 LIGAND | F. HOFFMANN-LA ROCHE AG (CH) | 2016-05-06 | — | — | WO | disclosed |
| EP-2428507-B1 | Cannabinoid receptor ligands | ABBVIE BAHAMAS LTD (BS) | 2015-10-21 | — | — | EP | disclosed |
| EP-2896615-A1 | Cannabinoid receptor ligands | AbbVie Bahamas Limited (BS) | 2015-07-22 | — | — | EP | disclosed |
| US-8288428-B2 | Compounds as cannabinoid receptor ligands | ABBOTT LABORATORIES (US) | 2012-10-16 | — | — | US | disclosed |
| US-8236822-B2 | Compounds as cannabinoid receptor ligands | ABBOTT LABORATORIES (US) | 2012-08-07 | — | — | US | disclosed |
| US-8188135-B2 | Compounds as cannabinoid receptor ligands | ABBOTT LABORATORIES (US) | 2012-05-29 | — | — | US | disclosed |
| EP-2428507-A2 | Cannabinoid receptor ligands | Abbott Laboratories (US) | 2012-03-14 | — | — | EP | disclosed |
| US-20100249086-A1 | Compounds As Cannabinoid Receptor Ligands | ABBOTT LABORATORIES (US) | 2010-09-30 | — | — | US | disclosed |
| US-20100249087-A1 | COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-09-30 | — | — | US | disclosed |
| US-20100069348-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-03-18 | — | — | US | disclosed |
| US-20100069349-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-03-18 | — | — | US | disclosed |
| US-20080312435-A1 | Imine Compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-12-18 | — | — | US | disclosed |
| EP-1820504-A1 | IMINE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2007-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312435-A1 | Imine Compound | CNR1, CNR2, HRH4 | MAPT 4160/4885MEN1 761/4885RAB9A 841/4885 |
| US-20100069348-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, NPY1R | MAPT 3688/4885MEN1 2912/4885RAB9A 915/4885 |
| US-20100069349-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, NPY1R | MAPT 3688/4885MEN1 2912/4885RAB9A 915/4885 |
| US-10227308-B2 | Radiolabeled cannabinoid receptor 2 ligand | CNR1, CNR2, GPR174 | MAPT 3573/4885MEN1 1177/4885RAB9A 1001/4885 |
| US-20100249087-A1 | COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, GPR18 | MAPT 2781/4885MEN1 2509/4885RAB9A 584/4885 |
| US-20100249086-A1 | Compounds As Cannabinoid Receptor Ligands | CNR1, CNR2, GPR18 | MAPT 2104/4885MEN1 1834/4885RAB9A 728/4885 |
| US-20170166534-A1 | RADIOLABELED CANNABINOID RECEPTOR 2 LIGAND | CNR1, CNR2, GPR174 | MAPT 3573/4885MEN1 1177/4885RAB9A 1001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.