Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 5/20 | 0.46 |
| ▸ | CHRM3 known ✓ | P20309 | 5/20 | 0.46 |
| ▸ | CHRM2 known ✓ | P08172 | 4/20 | 0.46 |
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.40 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.40 |
| ▸ | BDKRB2 known ✓ | P30411 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL543368 | 0.96 | THRB (0.50) | THRBCHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL1476296 | 0.95 | THRB (0.51) | THRBCHRM1CHRM3CHRM2CHRM4 | |
| Iodide SCHEMBL2252610 | 0.93 | THRB (0.50) | THRBCHRM1CHRM3CHRM2CHRM4 | |
| Fluoride Ion SCHEMBL28527581 | 0.93 | THRB (0.50) | THRBCHRM1CHRM3CHRM2CHRM4 | |
| Bromide SCHEMBL2252458 | 0.93 | THRB (0.50) | THRBCHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL21144533 | 0.93 | THRB (0.44) | THRBCHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL5183577 | 0.91 | THRB (0.47) | THRBCHRM1CHRM3CHRM2CHRM4 | |
| Ethyl Chloride SCHEMBL5032978 | 0.90 | THRB (0.47) | THRBCHRM1CHRM3CHRM2CHRM4 | |
| Sulfuric Acid SCHEMBL2793232 | 0.90 | THRB (0.47) | THRBCHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL28123075 | 0.89 | THRB (0.44) | THRBCHRM1CHRM3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106905935-B | Resin auxiliary agent composition and application thereof | 北京清水兰德油田技术服务有限公司 | 2019-04-09 | — | — | CN | disclosed |
| CN-106905935-A | Resin auxiliary agent composition and application thereof | 北京清水兰德油田技术服务有限公司 | 2017-06-30 | — | — | CN | disclosed |