Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7226169 | 0.77 | ALDH1A1 (0.42) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL24156632 | 0.76 | PARP2 (0.37) | MAPTL3MBTL1ALDH1A1KDM4ERAB9A | |
| SCHEMBL5431429 | 0.74 | ALDH1A1 (0.44) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL2252229 | 0.71 | MCHR1 (0.48) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL31511503 | 0.71 | MCHR1 (0.48) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL5696517 | 0.71 | ALDH1A1 (0.41) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL5189074 | 0.68 | POLB (0.44) | MAPTL3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL16533298 | 0.68 | S1PR4 (0.53) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL29131000 | 0.68 | MAPT (0.36) | MAPTL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL30602424 | 0.68 | MAPT (0.36) | MAPTL3MBTL1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377837-B | N (heteroaryl) sulfamide derivative as S100 inhibitor | 活跃生物技术有限公司 | 2017-08-04 | — | — | CN | disclosed |