Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29131000 | 1.00 | MAPT (0.36) | MAPTRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL30602330 | 0.79 | PGK1 (0.35) | MAPTRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL29130907 | 0.79 | PGK1 (0.35) | MAPTRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL29549875 | 0.74 | ALDH1A1 (0.45) | RAB9AKDM4ENPC1SMN1; SMN2PGK1 | |
| SCHEMBL29549876 | 0.74 | ALDH1A1 (0.45) | RAB9AKDM4ENPC1SMN1; SMN2PGK1 | |
| SCHEMBL2047755 | 0.74 | ALDH1A1 (0.45) | RAB9AKDM4ENPC1SMN1; SMN2PGK1 | |
| SCHEMBL12093320 | 0.72 | PGK1 (0.36) | MAPTRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL15687643 | 0.71 | GAA (0.42) | KDM4ENPC1PGK1CYP3A4AURKA | |
| SCHEMBL22042633 | 0.71 | CYP3A4 (0.37) | MAPTRAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL28163904 | 0.68 | MAPT (0.40) | MAPTRAB9AKDM4ENPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069724-A | Fused ring compounds, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-17 | — | — | CN | disclosed |