Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28164115 | 0.85 | GAA (0.61) | KDM1AMAOAGAAPARP14PARP1 | |
| SCHEMBL28242711 | 0.81 | OPRM1 (0.59) | OPRM1OPRD1OPRK1KCNH2KDM1A | |
| SCHEMBL4974021 | 0.79 | OPRM1 (0.56) | OPRM1OPRD1OPRK1KCNH2KDM1A | |
| SCHEMBL22112265 | 0.79 | IDO1 (0.43) | CYP2C9 | |
| Hydrochloric Acid SCHEMBL6393378 | 0.78 | OPRM1 (0.55) | OPRM1OPRD1OPRK1KCNH2KDM1A | |
| SCHEMBL1036815 | 0.77 | PARP1 (0.64) | OPRM1OPRD1PARP14PARP1 | |
| SCHEMBL27533679 | 0.77 | GBA1 (0.57) | — | |
| SCHEMBL6429862 | 0.75 | GAA (0.60) | OPRM1OPRD1OPRK1KCNH2GAA | |
| SCHEMBL28284087 | 0.74 | PARP14 (0.51) | OPRM1OPRD1OPRK1KCNH2KDM1A | |
| SCHEMBL7353600 | 0.72 | EED (0.57) | OPRM1OPRD1OPRK1KCNH2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106999450-A | immunomodulator | 弗莱塞斯生物科学公司 | 2017-08-01 | — | — | CN | disclosed |