Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.59 |
| ▸ | PPM1D | O15297 | 2/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.50 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005566 | 0.86 | PPM1D (0.64) | OPRM1OPRK1KCNH2OPRD1PPM1D | |
| SCHEMBL9005670 | 0.86 | PPM1D (0.64) | OPRM1OPRK1KCNH2OPRD1PPM1D | |
| SCHEMBL4974021 | 0.85 | OPRM1 (0.56) | OPRM1OPRK1KCNH2OPRD1CHEK2 | |
| SCHEMBL31277233 | 0.84 | NPC1 (0.56) | PPM1DPLAUNPC1EPHX1 | |
| Hydrochloric Acid SCHEMBL6393378 | 0.84 | OPRM1 (0.55) | OPRM1OPRK1KCNH2OPRD1CHEK2 | |
| SCHEMBL7353600 | 0.83 | EED (0.57) | OPRM1OPRK1KCNH2OPRD1CHEK2 | |
| SCHEMBL28164081 | 0.81 | OPRM1 (0.59) | OPRM1OPRK1KCNH2OPRD1GAA | |
| SCHEMBL6950371 | 0.79 | ERCC5 (0.51) | OPRM1OPRK1KCNH2OPRD1PPM1D | |
| SCHEMBL28284087 | 0.76 | PARP14 (0.51) | OPRM1OPRK1KCNH2OPRD1PARP1 | |
| SCHEMBL19444786 | 0.76 | HRH3 (0.50) | OPRM1OPRK1KCNH2OPRD1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440328-A | A kind of amide takes off boc-protected method | 常熟理工学院 | 2018-08-24 | — | — | CN | disclosed |