Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PTGES | O14684 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28165251 | 1.00 | LMNA (0.49) | LMNAPPARGPTGESALOX5PPARA | |
| SCHEMBL11217648 | 0.88 | LTB4R (0.47) | PPARGPTGESALOX5KMT2A | |
| SCHEMBL27995454 | 0.81 | KMT2A (0.55) | LMNASLC6A3SLC6A2SLC6A4KCNH2 | |
| SCHEMBL27487026 | 0.77 | PPARA (0.56) | LMNAPPARGPPARAPPARDSLC6A2 | |
| SCHEMBL15703029 | 0.76 | CYP1A2 (0.50) | LMNAPPARGPTGESALOX5PPARD | |
| SCHEMBL3485836 | 0.76 | L3MBTL1 (0.55) | PPARGPPARAPPARDL3MBTL1MAPT | |
| SCHEMBL15702931 | 0.76 | CYP1A2 (0.50) | LMNAPPARGPTGESALOX5PPARD | |
| SCHEMBL15118677 | 0.76 | CYP1A2 (0.53) | PPARDSLC6A3SLC6A2SLC6A4KCNH2 | |
| SCHEMBL9689273 | 0.75 | L3MBTL1 (0.69) | LMNAPPARDSLC6A3L3MBTL1MAPT | |
| SCHEMBL27795423 | 0.75 | LMNA (0.48) | LMNAPOLBL3MBTL1MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074887-A | Substituted-dihydro pyrrolo-pyrazole compound | 宇部兴产株式会社 | 2017-08-18 | — | — | CN | disclosed |