Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29318689 | 0.85 | SLC6A3 (0.52) | SLC6A3TAAR1KCNH2 | |
| SCHEMBL28900236 | 0.77 | DRD2 (0.46) | — | |
| SCHEMBL18398981 | 0.77 | DRD2 (0.49) | — | |
| SCHEMBL16517709 | 0.77 | DRD2 (0.46) | — | |
| SCHEMBL2959126 | 0.75 | PRKACA (0.44) | — | |
| SCHEMBL22089840 | 0.75 | DRD2 (0.41) | — | |
| SCHEMBL27871750 | 0.74 | SLC6A3 (0.46) | SLC6A3TAAR1KCNH2 | |
| SCHEMBL27988602 | 0.74 | SLC6A3 (0.46) | SLC6A3TAAR1 | |
| SCHEMBL1663372 | 0.74 | — | — | |
| SCHEMBL23877797 | 0.73 | DRD2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103649053-B | Aminomethyl quinolone compounds | 霍夫曼-拉罗奇有限公司 | 2017-07-04 | — | — | CN | disclosed |