SCHEMBL28166201

SCHEMBL28166201

CC1OC(C)(C)OCC1C(=O)Cl

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.31
CA1 P00915 1/20 0.31
TMEM97 Q5BJF2 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
HCRTR1 O43613 1/20 0.30
HCRTR2 O43614 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11903395 0.82 HCRTR2 (0.33) CA2TMEM97SIGMAR1HCRTR1HCRTR2
SCHEMBL28304852 0.79 CA2 (0.33) CA2
SCHEMBL5011018 0.74 CA2 (0.33) CA2CA1TMEM97SIGMAR1HCRTR1
SCHEMBL4014633 0.74 CA2 (0.33) CA2CA1TMEM97SIGMAR1HCRTR1
SCHEMBL7078356 0.74 CA2 (0.33) CA2CA1TMEM97SIGMAR1HCRTR1
SCHEMBL26535538 0.69 APLNR (0.31) HCRTR1HCRTR2
SCHEMBL8532103 0.68 CA2 (0.33) CA2
SCHEMBL26751479 0.68 CA2 (0.33) CA2
SCHEMBL4411311 0.67 MAPK1 (0.36)
SCHEMBL28138085 0.67 CA2 (0.34) CA2CA1TMEM97SIGMAR1HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104109146-B Stilbene compound as carcinoma squamosum and liver cancer inhibitor and application thereof 中国医药大学 2017-09-01 CN disclosed