Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014633 | 1.00 | CA2 (0.33) | CA2TMEM97SIGMAR1HCRTR2HCRTR1 | |
| SCHEMBL7078356 | 1.00 | CA2 (0.33) | CA2TMEM97SIGMAR1HCRTR2HCRTR1 | |
| SCHEMBL1826271 | 0.82 | CA2 (0.35) | CA2TMEM97SIGMAR1HCRTR2HCRTR1 | |
| SCHEMBL3020689 | 0.82 | CA2 (0.35) | CA2TMEM97SIGMAR1HCRTR2HCRTR1 | |
| SCHEMBL883211 | 0.82 | CA2 (0.35) | CA2TMEM97SIGMAR1HCRTR2HCRTR1 | |
| SCHEMBL1030223 | 0.80 | HCRTR2 (0.39) | CA2TMEM97SIGMAR1HCRTR2HCRTR1 | |
| SCHEMBL2038232 | 0.80 | HCRTR2 (0.39) | CA2TMEM97SIGMAR1HCRTR2HCRTR1 | |
| SCHEMBL1030224 | 0.80 | HCRTR2 (0.39) | CA2TMEM97SIGMAR1HCRTR2HCRTR1 | |
| SCHEMBL8875465 | 0.80 | CA2 (0.34) | CA2TMEM97SIGMAR1HCRTR2HCRTR1 | |
| SCHEMBL9162631 | 0.78 | HCRTR2 (0.38) | CA2TMEM97SIGMAR1HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180193315-A1 | SPIROCYCLIC HAT INHIBITORS AND METHODS FOR THEIR USE | ABBVIE INC (US) | 2018-07-12 | — | — | US | disclosed |
| US-20180071262-A1 | SPIROCYCLIC HAT INHIBITORS AND METHODS FOR THEIR USE | ABBVIE INC. (US) | 2018-03-15 | — | — | US | disclosed |
| US-20160235716-A1 | SPIROCYCLIC HAT INHIBITORS AND METHODS FOR THEIR USE | ABBVIE INC. (US) | 2016-08-18 | — | — | US | disclosed |
| US-9408919-B2 | Biodegradable polymer—bioactive moiety conjugates | POLYACTIVA PTY LTD. (AU) | 2016-08-09 | — | — | US | disclosed |
| US-9408919-B2 | Biodegradable polymer—bioactive moiety conjugates | POLYACTIVA PTY LTD. (AU) | 2016-08-09 | — | — | US | disclosed |
| WO-2016044770-A1 | SPIROCYCLIC HAT INHIBITORS AND METHODS FOR THEIR USE | ABBVIE INC. (US) | 2016-03-24 | — | — | WO | disclosed |
| US-20140120058-A1 | POLYMER CONJUGATED PROSTAGLANDIN ANALOGUES | POLYACTIVA PTY LTD | 2014-05-01 | — | — | US | disclosed |
| US-20140120058-A1 | POLYMER CONJUGATED PROSTAGLANDIN ANALOGUES | POLYACTIVA PTY LTD | 2014-05-01 | — | — | US | disclosed |
| US-20140046018-A1 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES | POLYACTIVA PTY LTD. (AU) | 2014-02-13 | — | — | US | disclosed |
| US-20140046018-A1 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES | POLYACTIVA PTY LTD. (AU) | 2014-02-13 | — | — | US | disclosed |
| WO-2000037115-A1 | WATER-SOLUBLE CONTRAST MEDIA FOR X-RAY IMAGING | NYCOMED IMAGING AS (NO) | 2000-06-29 | — | — | WO | disclosed |
| US-5993780-A | A POLYIODOARYLALKYL ALCOHOL OR DERIVATIVE | NYCOMED IMAGING AS (NO) | 1999-11-30 | — | — | US | disclosed |
| EP-0782564-B1 | IODINATED X-RAY CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1999-09-01 | — | — | EP | disclosed |
| US-5882628-A | Contrast media | NYCOMED IMAGING AS (NO) | 1999-03-16 | — | — | US | disclosed |
| CN-1166826-A | Iodo-substituted X-ray contrast agents | NYCOMED IMAGING AS (NO) | 1997-12-03 | — | — | CN | disclosed |
| EP-0782564-A1 | IODINATED X-RAY CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1997-07-09 | — | — | EP | disclosed |
| US-5641428-A | SHORT SWITCHING TIMES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-24 | — | — | US | disclosed |
| WO-1996009282-A1 | IODINATED X-RAY CONTRAST MEDIA | NYCOMED IMAGING A/S (NO) | 1996-03-28 | — | — | WO | disclosed |
| US-4954642-A | INOTROPIC, HYPOTENSIVE | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1990-09-04 | — | — | US | disclosed |
| EP-0222413-A2 | Novel forskolin derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1987-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160235716-A1 | SPIROCYCLIC HAT INHIBITORS AND METHODS FOR THEIR USE | KAT2B, HDAC1, HDAC9 | CA2 2250/4885TMEM97 3135/4885SIGMAR1 2184/4885 |
| US-20140046018-A1 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES | BMP2, MKI67, FGF2 | CA2 3442/4885TMEM97 4411/4885SIGMAR1 3025/4885 |
| US-20140120058-A1 | POLYMER CONJUGATED PROSTAGLANDIN ANALOGUES | PTGIS, PTGS2, PTGES | CA2 1280/4885TMEM97 3091/4885SIGMAR1 3778/4885 |
| US-20180193315-A1 | SPIROCYCLIC HAT INHIBITORS AND METHODS FOR THEIR USE | KAT2B, HDAC1, KAT2A | CA2 2193/4885TMEM97 3334/4885SIGMAR1 2301/4885 |
| US-20180071262-A1 | SPIROCYCLIC HAT INHIBITORS AND METHODS FOR THEIR USE | KAT2B, HDAC1, HDAC9 | CA2 2250/4885TMEM97 3135/4885SIGMAR1 2184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.