Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28166385

COC(=O)CC(O)(CC(=O)OC)C(=O)OC.N

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
LMNA P02545 3/20 0.40
USP2 O75604 1/20 0.40
HSD17B10 Q99714 3/20 0.39
GAA P10253 2/20 0.39
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
TET2 Q6N021 1/20 0.37
RECQL P46063 2/20 0.35
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
HPGD P15428 1/20 0.34
ALDH1A1 P00352 2/20 0.33
DGAT1 O75907 1/20 0.33
SRC P12931 1/20 0.31
CA12 O43570 1/20 0.31
CA14 Q9ULX7 1/20 0.31
KDM4E B2RXH2 1/20 0.31
KCNN4 O15554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL168730 0.98 TSHR (0.43) TSHRLMNAUSP2HSD17B10GAA
Methoxymethane SCHEMBL28184894 0.95 TSHR (0.42) TSHRLMNAUSP2HSD17B10GAA
SCHEMBL14849447 0.89 MGAM (0.44) TSHRLMNAUSP2HSD17B10GAA
SCHEMBL23330 0.89 ALDH1A1 (0.44) TSHRLMNAUSP2HSD17B10GAA
SCHEMBL1812866 0.86 TSHR (0.39) TSHRLMNAUSP2HSD17B10GAA
SCHEMBL13399022 0.86 USP2 (0.36) TSHRLMNAUSP2HSD17B10GAA
SCHEMBL28483049 0.86 DGAT1 (0.45) TSHRLMNAUSP2HSD17B10GAA
SCHEMBL18120860 0.86 LMNA (0.39) TSHRLMNAUSP2HSD17B10GAA
SCHEMBL5399544 0.86 LMNA (0.39) TSHRLMNAUSP2HSD17B10GAA
SCHEMBL2869333 0.86 CA4 (0.48) TSHRLMNAUSP2HSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117440991-A Polysiloxane composition 默克专利有限公司 2024-01-23 CN disclosed
CN-115315252-A Antiviral composition for preventing or treating infection or respiratory disease after exposure 盈擘医药股份有限公司 2022-11-08 CN disclosed
CN-114040750-A Inhalable bronchodilator sustained-release composition for treating pulmonary diseases 盈擘医药股份有限公司 2022-02-11 CN disclosed
CN-108601746-A MESOPOROUS SILICA NANOPARTICLES WITH LIPID BILAYER COATING FOR CARGO DELIVERY 加利福尼亚大学董事会 2018-09-28 CN disclosed
CN-107004912-A Electrolyte and metal hydride battery 巴斯夫公司 2017-08-01 CN disclosed