Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28662301 | 0.79 | KDM4E (0.57) | KDM4EGAAMAPTHTR2AMAPK1 | |
| SCHEMBL28311309 | 0.79 | KDM4E (0.57) | KDM4EGAAMAPTHTR2AMAPK1 | |
| SCHEMBL16056064 | 0.77 | ALDH1A1 (0.51) | KDM4EGAAHTR2AALDH1A1HPGD | |
| SCHEMBL16056426 | 0.77 | HTR2A (0.35) | KDM4EMAPTHTR2AMAPK1CASP1 | |
| SCHEMBL16056256 | 0.75 | TDP1 (0.49) | KDM4EGAAMAPTCASP1ALDH1A1 | |
| SCHEMBL16056393 | 0.74 | ALDH1A1 (0.49) | KDM4EGAAHTR2AMAPK1ALDH1A1 | |
| SCHEMBL10303267 | 0.74 | FPR2 (0.39) | KDM4EGAAMAPTHTR2ACALM1 | |
| SCHEMBL22029967 | 0.74 | MAPT (0.70) | KDM4EGAAMAPTHTR2AMAPK1 | |
| SCHEMBL28848463 | 0.73 | GAA (0.44) | GAAMAPTHTR2AALDH1A1HPGD | |
| SCHEMBL17535937 | 0.73 | HTR2A (0.39) | MAPTHTR2AMAPK1ALDH1A1APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612158-B | The somatostatin receptor hypotype 5 (SSTR5) antagonist | 武田药品工业株式会社 | 2017-06-30 | — | — | CN | disclosed |