Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20259973 | 0.86 | POLB (0.40) | GAAPOLBGFERHTR2AALDH1A1 | |
| SCHEMBL2953510 | 0.76 | GAA (0.59) | GAAPOLBGFERALDH1A1MEN1 | |
| SCHEMBL20073796 | 0.74 | QDPR (0.46) | GAAPOLBGFERHTR2A | |
| SCHEMBL12889915 | 0.74 | GAA (0.57) | GAAPOLBGFERHTR2AALDH1A1 | |
| SCHEMBL28166402 | 0.73 | KDM4E (0.45) | GAAHTR2AALDH1A1TSHRMAPT | |
| SCHEMBL30888631 | 0.72 | HTR2C (0.53) | GAAHTR2AALDH1A1HTR2CTSHR | |
| SCHEMBL14200081 | 0.72 | GAA (0.57) | GAAPOLBGFERHTR2AALDH1A1 | |
| SCHEMBL2966137 | 0.72 | MAOA (0.42) | GAAPOLBGFERHTR2AALDH1A1 | |
| SCHEMBL27102693 | 0.72 | P2RX3 (0.42) | GAAPOLBGFERP2RX3P2RX2 | |
| SCHEMBL21145969 | 0.70 | MMP13 (0.43) | POLBALDH1A1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612158-B | The somatostatin receptor hypotype 5 (SSTR5) antagonist | 武田药品工业株式会社 | 2017-06-30 | — | — | CN | disclosed |