Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28166457

COB(O)c1ccccc1.N

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 4/20 0.48
ORAI1 Q96D31 4/20 0.48
ORAI2 Q96SN7 4/20 0.48
ORAI3 Q9BRQ5 4/20 0.48
TRPV6 Q9H1D0 4/20 0.48
CA4 P22748 2/20 0.48
PCSK9 Q8NBP7 2/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA14 Q9ULX7 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
MGLL Q99685 2/20 0.37
LTA4H P09960 1/20 0.36
TSHR P16473 1/20 0.34
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
TRPA1 O75762 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL691860 0.97 ENPP2 (0.50) ENPP2ORAI1ORAI2ORAI3TRPV6
Water SCHEMBL28105163 0.95 ENPP2 (0.48) ENPP2ORAI1ORAI2ORAI3TRPV6
Ethylene Glycol SCHEMBL28307523 0.89 ENPP2 (0.42) ENPP2ORAI1ORAI2ORAI3TRPV6
Pyridine SCHEMBL29132336 0.85 ENPP2 (0.39) ENPP2ORAI1ORAI2ORAI3TRPV6
SCHEMBL14819206 0.84 MGLL (0.58) ENPP2ORAI1ORAI2ORAI3TRPV6
SCHEMBL22212886 0.81 CA1 (0.64) ENPP2CA4CA1CA2LTA4H
SCHEMBL22960747 0.79 MGLL (0.62) ENPP2ORAI1ORAI2ORAI3TRPV6
SCHEMBL13686655 0.78 CA1 (0.67) ENPP2CA7CA14CA1CA2
SCHEMBL262207 0.78 ENPP2 (0.46) ENPP2ORAI1ORAI2ORAI3TRPV6
Fluoride SCHEMBL28835775 0.76 ENPP2 (0.44) ENPP2ORAI1ORAI2ORAI3TRPV6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107129580-A A kind of dynamic aggregation thing material and its application 翁秋梅 2017-09-05 CN disclosed