SCHEMBL262207

SCHEMBL262207

COOB(O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 4/20 0.46
ORAI1 Q96D31 4/20 0.46
ORAI2 Q96SN7 4/20 0.46
ORAI3 Q9BRQ5 4/20 0.46
TRPV6 Q9H1D0 4/20 0.46
CA4 P22748 2/20 0.46
PCSK9 Q8NBP7 2/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
MGLL Q99685 2/20 0.35
LTA4H P09960 1/20 0.34
TSHR P16473 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL28835775 0.98 ENPP2 (0.44) ENPP2ORAI1ORAI2ORAI3TRPV6
Tetrahydrofuran SCHEMBL28301963 0.85 CA4 (0.34) ENPP2ORAI1ORAI2ORAI3TRPV6
SCHEMBL28107366 0.81 ENPP2 (0.37) ENPP2ORAI1ORAI2ORAI3TRPV6
SCHEMBL691860 0.80 ENPP2 (0.50) ENPP2ORAI1ORAI2ORAI3TRPV6
SCHEMBL28135433 0.79 CYP2D6 (0.37) TSHR
Water SCHEMBL28105163 0.78 ENPP2 (0.48) ENPP2ORAI1ORAI2ORAI3TRPV6
Ammonia Solution, Strong SCHEMBL28166457 0.78 ENPP2 (0.48) ENPP2ORAI1ORAI2ORAI3TRPV6
SCHEMBL28097813 0.77 CYP1A2 (0.32) ENPP2CA1CA2
SCHEMBL26924069 0.77 ORAI1 (0.50) ENPP2ORAI1ORAI2ORAI3TRPV6
SCHEMBL3985882 0.77 ACHE (0.41) ENPP2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 548 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12188898-B2 Non-enzymatic electrochemical sensor for measuring analytes TERUMO KABUSHIKI KAISHA (JP) 2025-01-07 US claimed
CN-114907312-B Diaryl ethylene organic compound, preparation method thereof and application thereof in anti-counterfeiting 中国计量大学 2024-07-05 CN claimed
CN-113621215-B Preparation method of organic-inorganic hybrid biomass phenolic resin ablation-resistant material 哈尔滨工业大学 2024-02-09 CN claimed
US-20240019396-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES TERUMO KABUSHIKI KAISHA (JP) 2024-01-18 US claimed
CN-117209367-A Fluorenyl bisphenol monomer and fluorenyl polyarylether resin, and preparation method and application thereof 大连理工大学 2023-12-12 CN claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
CN-116916755-A Materials and methods for extending the shelf life of food products JP实验室公司 2023-10-20 CN claimed
CN-115784848-A Nor-sorbosone derivative and preparation method and application thereof 成都理工大学 2023-03-14 CN claimed
CN-114907312-A Diaryl ethylene organic compound, preparation method thereof and application thereof in anti-counterfeiting 中国计量大学 2022-08-16 CN claimed
CN-114736414-A Preparation method of hydrophilic polystyrene microspheres 南京亘闪生物科技有限公司 2022-07-12 CN claimed
CN-101367741-A 4'-methoxy-2-amino--5-acetyl biphenyl and synthesis thereof UNIV SHANGHAI (CN) 2009-02-18 CN claimed
CN-101225026-A Fluoro-4, 4' -biphenol bis allyl ether and synthetic method thereof YANTAI VALIANT FINE CHEMICALS (CN) 2008-07-23 CN claimed
EP-1313560-A4 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION UNIV YALE (US) 2005-02-09 EP claimed
CN-1122672-C Process for the preparation of azacyclohexapeptides MERCK & CO INC (US) 2003-10-01 CN claimed
EP-1313560-A1 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION YALE UNIVERSITY (US) 2003-05-28 EP claimed
WO-2002011883-A1 CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION YALE UNIVERSITY (US) 2002-02-14 WO claimed
EP-1107982-A1 REVERSIBLE BORONATE COMPLEXES OF 1,2-$i(CIS)-DIOL CYCLIC-PEPTIDES Eli Lilly & Company (US) 2001-06-20 EP claimed
WO-2000012540-A1 REVERSIBLE BORONATE COMPLEXES OF 1,2-CIS-DIOL CYCLIC-PEPTIDES ELI LILLY AND COMPANY (US) 2000-03-09 WO claimed
WO-2000010007-A2 DEVICES AND METHODS FOR ANALYSIS OF NON-IONIC SOLUTES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-02-24 WO claimed
CN-1222161-A Process for preparing certain aza cyclohexapeptides MERCK & CO INC (US) 1999-07-07 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240019396-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES SPR, SRR, BLVRB ENPP2 1154/4885ORAI1 2446/4885ORAI2 2680/4885
US-12188898-B2 Non-enzymatic electrochemical sensor for measuring analytes SPR, SRR, BLVRB ENPP2 1154/4885ORAI1 2446/4885ORAI2 2680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.