SCHEMBL28166756

SCHEMBL28166756

C=Cc1ccc(C=C)c(-c2ccccc2)c1C=C

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
TSHR P16473 1/20 0.37
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36
BRD4 O60885 1/20 0.31
BRD2 P25440 1/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28992715 0.86 ALDH1A1 (0.33) ALDH1A1TSHRLMNAMAPTHTT
SCHEMBL27667543 0.85 NFE2L2 (0.39) ALDH1A1TSHRLMNA
SCHEMBL29044990 0.84 ALDH1A1 (0.32) ALDH1A1TSHRLMNAMAPTHTT
SCHEMBL29155308 0.84 BRD4 (0.35) ALDH1A1TSHRLMNAMAPTHTT
SCHEMBL27675760 0.79 ALDH1A1 (0.46) ALDH1A1TSHRLMNAMAPTHTT
SCHEMBL31432621 0.77 ALDH1A1 (0.37) ALDH1A1TSHRLMNA
SCHEMBL8848267 0.77 ALDH1A1 (0.37) ALDH1A1TSHRLMNA
SCHEMBL4069489 0.77 ALDH1A1 (0.36) ALDH1A1TSHRLMNAMAPTHTT
SCHEMBL9617660 0.77 ALDH1A1 (0.36) ALDH1A1TSHRLMNAMAPTHTT
SCHEMBL4071671 0.77 ALDH1A1 (0.43) ALDH1A1TSHRLMNAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106999366-A It is used as viscosity intensifier, matte effect agent and/or the hydrogel or water alcogel of the synthesis phyllosilicate for applying homogenizing agent 欧莱雅 2017-08-01 CN disclosed