SCHEMBL4069489

SCHEMBL4069489

C=Cc1ccc(-c2ccccc2)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.36
TSHR P16473 1/20 0.36
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
FLT3 P36888 2/20 0.33
BACE1 P56817 1/20 0.33
ALOX5 P09917 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
HDAC4 P56524 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HSD17B10 Q99714 2/20 0.32
HPGD P15428 2/20 0.32
BCL2L1 Q07817 1/20 0.32
CYP2A6 P11509 1/20 0.32
MAPK1 P28482 1/20 0.32
PELI1 Q96FA3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4066882 0.90 FLT3 (0.34) ALDH1A1TSHRLMNAMAPTHTT
SCHEMBL4075472 0.87 MAOA (0.34) ALDH1A1LMNAMAPTHTTBACE1
SCHEMBL28992715 0.84 ALDH1A1 (0.33) ALDH1A1TSHRLMNAMAPTHTT
SCHEMBL4067689 0.83 ALDH1A1 (0.40) ALDH1A1TSHRLMNAMAPTHTT
SCHEMBL29044990 0.82 ALDH1A1 (0.32) ALDH1A1TSHRLMNAMAPTHTT
SCHEMBL27612235 0.82 ALDH1A1 (0.38) ALDH1A1TSHRLMNAMAPTHTT
SCHEMBL27763811 0.82 BACE1 (0.37) ALDH1A1TSHRLMNAMAPTHTT
SCHEMBL9613858 0.82 ALDH1A1 (0.39) ALDH1A1TSHRLMNAMAPTHTT
Ammonia Solution, Strong SCHEMBL27824730 0.82 ALDH1A1 (0.39) ALDH1A1TSHRLMNAMAPTHTT
SCHEMBL9617660 0.79 ALDH1A1 (0.36) ALDH1A1TSHRLMNAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101889959-A Be used to improve the encapsulated fluorescent whitening compositions of appearance CIBA SC HOLDING AG 2010-11-24 CN claimed
CN-1993099-A Encapsulated fluorescent whitening compositions for enhancing surface appearance CIBA SC HOLDING AG (CH) 2007-07-04 CN claimed
US-6080819-A Blends of olefin polymers and syndiotactic vinyl polymers BOREALIS AG (AT) 2000-06-27 US claimed
EP-4314118-A1 POLYSILOXANE VINYLIC CROSSLINKERS WITH HIGH REFRACTIVE INDEX Alcon Inc. (CH) 2024-02-07 EP disclosed
CN-116888193-A Polysiloxane vinyl cross-linking agent with high refractive index 爱尔康公司 2023-10-13 CN disclosed
EP-2019120-B1 BLOCK COPOLYMERS NIPPON SODA CO (JP) 2016-04-13 EP disclosed
WO-2015023001-A1 NOVEL ORGANOPOLYSILOXANE, SURFACE TREATMENT AGENT COMPRISING THE SAME, RESIN COMPOSITION COMPRISING THE SAME, AND GELATINOUS PRODUCT OR CURED PRODUCT THEREOF DOW CORNING TORAY CO., LTD. (JP) 2015-02-19 WO disclosed
US-8193285-B2 Block copolymers NIPPON SODA CO., LTD. (JP) 2012-06-05 US disclosed
CN-101889959-A Be used to improve the encapsulated fluorescent whitening compositions of appearance CIBA SC HOLDING AG 2010-11-24 CN disclosed
US-20090253867-A1 BLOCK COPOLYMERS NIPPON SODA CO., LTD. (JP) 2009-10-08 US disclosed
EP-2019120-A1 BLOCK COPOLYMERS Nippon Soda Co., Ltd. (JP) 2009-01-28 EP disclosed
US-4090959-A A PHOSPHONATE-SUBSTITUTED METHANESULFONAMIDE HOOKER CHEMICALS & PLASTICS CORP. (US) 1978-05-23 US disclosed
US-4055591-A METAL ION SEQUESTRANTS, FLAME RETARDANTS HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-10-25 US disclosed
US-4053450-A DIALKYL ALKYL AND CYCLIC PHOSPHORAMIDOMETHYL PHOSPHONATES HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-10-11 US disclosed
US-4018560-A FIREPROOFING TEXTILES HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-04-19 US disclosed
US-3992294-A UREAPHOSPHONATES HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-11-16 US disclosed
US-3976620-A Phosphorus containing amides flame retardants HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-08-24 US disclosed
US-3959551-A TEXTILE, FIREPROOFING HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-05-25 US disclosed
US-3939226-A SEQUESTRANT, FIRE RETARDANT HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-02-17 US disclosed
US-3935162-A Dialkyl aromatic amidomethyl phosphonate flame retardants HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-01-27 US disclosed