Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPN | P05981 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22310126 | 0.84 | HTR2B (0.43) | HTR2BPOLBMAOAALDH1A1MAPT | |
| SCHEMBL8160473 | 0.77 | MAOA (0.42) | HTR2BPOLBMAOAALDH1A1MAPT | |
| SCHEMBL19682354 | 0.74 | CYP1A2 (0.41) | HTR2BPOLBMAOAALDH1A1MAPT | |
| SCHEMBL7603978 | 0.70 | MAOA (0.40) | HTR2BPOLBMAOAALDH1A1MAPT | |
| SCHEMBL30403300 | 0.70 | MAOA (0.56) | HTR2BPOLBMAOAALDH1A1MAPT | |
| SCHEMBL1626146 | 0.70 | MAOA (0.52) | HTR2BPOLBMAOAALDH1A1MAPT | |
| SCHEMBL11814243 | 0.70 | MAOA (0.46) | HTR2BPOLBMAOAALDH1A1MAPT | |
| SCHEMBL3787825 | 0.70 | MAOA (0.46) | HTR2BPOLBMAOAALDH1A1MAPT | |
| SCHEMBL1626149 | 0.70 | MAPT (0.61) | HTR2BPOLBMAOAALDH1A1MAPT | |
| Fluorene SCHEMBL8180 | 0.69 | MAOA (0.68) | HTR2BMAOAALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106977410-A | One kind prepares lumefantrine intermediate α by fluorenes（Di-n-butylamine base）The preparation method of 2,7 dichloro-4,4 fluorenemethanols | 张家港威胜生物医药有限公司 | 2017-07-25 | — | — | CN | disclosed |