SCHEMBL1626149

SCHEMBL1626149

Oc1cccc2c1-c1ccccc1C2

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.61
ALDH1A1 P00352 4/20 0.61
ALOX15 P16050 3/20 0.61
HSD17B10 Q99714 3/20 0.61
TDP1 Q9NUW8 3/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
TSHR P16473 2/20 0.61
USP2 O75604 2/20 0.61
CYP3A4 P08684 2/20 0.61
THRB P10828 2/20 0.61
HPN P05981 1/20 0.61
ALOX5 P09917 1/20 0.61
PTGS1 P23219 1/20 0.61
PDE4A P27815 1/20 0.61
KDR P35968 1/20 0.61
SIRT5 Q9NXA8 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
HRH3 Q9Y5N1 1/20 0.61
MAOA P21397 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30844848 1.00 MAPT (0.61) MAPTALDH1A1ALOX15HSD17B10TDP1
SCHEMBL16245359 0.88 ALDH1A1 (0.52) MAPTALDH1A1ALOX15HSD17B10TDP1
SCHEMBL29359219 0.88 ALDH1A1 (0.52) MAPTALDH1A1ALOX15HSD17B10TDP1
SCHEMBL1204733 0.84 MAPT (0.75) MAPTALDH1A1ALOX15HSD17B10TDP1
SCHEMBL29549838 0.84 MAPT (0.75) MAPTALDH1A1ALOX15HSD17B10TDP1
SCHEMBL12023167 0.84 ALDH1A1 (0.74) MAPTALDH1A1ALOX15HSD17B10TDP1
Fluorene SCHEMBL28466769 0.81 MAOA (0.54) MAPTALDH1A1ALOX15HSD17B10TDP1
SCHEMBL31727528 0.80 MEN1 (0.53) MAPTALDH1A1ALOX15HSD17B10TDP1
SCHEMBL20918664 0.79 DRD3 (0.44) MAPTALDH1A1ALOX15HSD17B10TDP1
SCHEMBL7535295 0.79 MAOA (0.48) MAPTALDH1A1ALOX15HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3424907-B1 CONNECTIONS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2025-03-12 EP claimed
US-11997922-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2024-05-28 US claimed
US-20230217811-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-07-06 US claimed
US-11641775-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2023-05-02 US claimed
US-11056652-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2021-07-06 US claimed
US-20210151682-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-05-20 US claimed
US-10944058-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2021-03-09 US claimed
EP-3345984-B1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-03-04 EP claimed
US-20190288209-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-09-19 US claimed
US-10355217-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2019-07-16 US claimed
CN-105980518-B Compound and organic electronic device 默克专利有限公司 2019-07-12 CN claimed
CN-108863814-A Fluorenes and electronic device containing the fluorenes 默克专利有限公司 2018-11-23 CN claimed
EP-2875004-B1 FLUORENES AND ELECTRONIC DEVICES CONTAINING THEM MERCK PATENT GMBH (DE) 2018-07-18 EP claimed
EP-3077477-B1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-02-28 EP claimed
US-9882142-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2018-01-30 US claimed
US-20160301005-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-10-13 US claimed
US-20150179940-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-06-25 US claimed
US-3947468-A Production of dibenzopyrans, their isomeric fluorenols and dibenzothiopyrans GENERAL ELECTRIC COMPANY (US) 1976-03-30 US claimed
US-12503480-B2 Cyclic phosphazene compound having oxaphosphorin ring-containing structure FUSHIMI PHARMACEUTICAL CO., LTD. (JP) 2025-12-23 US disclosed
WO-1999014217-A1 ARYLOXYMETHYL CARBAPENEM ANTIBACTERIALS MERCK & CO., INC. (US) 1999-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10355217-B2 Compounds and organic electronic devices ETV6, AFF2, CYP2C19 MAPT 1891/4885ALDH1A1 459/4885ALOX15 765/4885
US-10944058-B2 Compounds and organic electronic devices ETV6, CYP2C19, AFF2 MAPT 1886/4885ALDH1A1 408/4885ALOX15 731/4885
US-11056652-B2 Compounds and organic electronic devices ETV6, AFF2, CYP2C19 MAPT 1891/4885ALDH1A1 459/4885ALOX15 765/4885
US-20230217811-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES ETV6, CYP2C19, AFF2 MAPT 1886/4885ALDH1A1 408/4885ALOX15 731/4885
US-20210151682-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES ETV6, CYP2C19, AFF2 MAPT 1886/4885ALDH1A1 408/4885ALOX15 731/4885
US-11641775-B2 Compounds and organic electronic devices ETV6, CYP2C19, AFF2 MAPT 1886/4885ALDH1A1 408/4885ALOX15 731/4885
US-20190288209-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES ETV6, AFF2, CYP2C19 MAPT 1891/4885ALDH1A1 459/4885ALOX15 765/4885
US-20150179940-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES ETV6, CYP2C19, AFF2 MAPT 1886/4885ALDH1A1 408/4885ALOX15 731/4885
US-12503480-B2 Cyclic phosphazene compound having oxaphosphorin ring-containing structure PFAS, PHOSPHO1, PAF1 MAPT 3822/4885ALDH1A1 1437/4885ALOX15 892/4885
US-11997922-B2 Compounds and organic electronic devices ETV6, CYP2C19, AFF2 MAPT 1886/4885ALDH1A1 408/4885ALOX15 731/4885
US-20160301005-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES ETV6, AFF2, CYP2C19 MAPT 1891/4885ALDH1A1 459/4885ALOX15 765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.