Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.73 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6246105 | 0.85 | RIPK1 (0.66) | RIPK1SCD5TSHRHSP90AA1HSP90AB1 | |
| SCHEMBL28168147 | 0.83 | HSP90AA1 (0.56) | RIPK1HSP90AA1HSP90AB1 | |
| SCHEMBL469686 | 0.83 | RIPK1 (0.73) | RIPK1SCD5TSHROPRK1JAK2 | |
| SCHEMBL17067870 | 0.83 | RIPK1 (0.73) | RIPK1SCD5TSHROPRK1JAK2 | |
| SCHEMBL17067869 | 0.83 | RIPK1 (0.73) | RIPK1SCD5TSHROPRK1JAK2 | |
| SCHEMBL17881986 | 0.82 | RIPK1 (0.80) | RIPK1SCD5TSHROPRK1OPRM1 | |
| SCHEMBL19500978 | 0.82 | RIPK1 (0.65) | RIPK1SCD5TSHRTACR1OPRK1 | |
| SCHEMBL19500979 | 0.82 | RIPK1 (0.65) | RIPK1SCD5TSHRTACR1OPRK1 | |
| SCHEMBL28149188 | 0.81 | TRPA1 (0.53) | RIPK1SCD5TACR1 | |
| SCHEMBL17881903 | 0.81 | RIPK1 (0.60) | RIPK1SCD5TSHROPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108492-A | Inhibitor of cellular necrosis | 北京生命科学研究所 | 2017-08-29 | — | — | CN | disclosed |