Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | GLB1 | P16278 | 1/20 | 0.32 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.32 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28848848 | 0.84 | MAPT (0.47) | THRBNPC1LMNAMAPTHPGD | |
| SCHEMBL28966853 | 0.74 | HTT (0.61) | NPC1LMNAMAPTHPGDNFKB1 | |
| SCHEMBL4701487 | 0.73 | NPC1 (0.39) | NPC1LMNAMAPTHPGDNFKB1 | |
| SCHEMBL5698975 | 0.73 | NPC1 (0.46) | NPC1LMNAMAPTHPGDNFKB1 | |
| SCHEMBL1119186 | 0.71 | NPC1 (0.51) | THRBNPC1MAPTRAB9ATDP1 | |
| SCHEMBL20828630 | 0.71 | POLB (0.57) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL20866071 | 0.70 | SLC7A5 (0.51) | THRBESR1SLC6A2ESR2 | |
| SCHEMBL4580087 | 0.70 | POLB (0.60) | THRBMAPTTDP1POLBAPEX1 | |
| SCHEMBL4541500 | 0.70 | ESR1 (0.62) | THRBNPC1LMNAMAPTRAB9A | |
| SCHEMBL28694550 | 0.69 | TSHR (0.49) | THRBNPC1LMNAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103869623-B | Coating composition | 默克专利有限公司 | 2017-07-21 | — | — | CN | disclosed |