Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28167692 | 0.84 | THRB (0.38) | MAPTRAB9ANPC1CA1CA2 | |
| SCHEMBL5699058 | 0.80 | RAB9A (0.56) | MAPTRAB9ANPC1ACHECA12 | |
| SCHEMBL4698545 | 0.78 | RAB9A (0.50) | MAPTRAB9ANPC1ACHECA12 | |
| SCHEMBL217658 | 0.77 | MAPT (0.47) | MAPTRAB9ANPC1ACHECA12 | |
| SCHEMBL21868936 | 0.76 | CA1 (0.51) | MAPTRAB9ANPC1CA12CA1 | |
| SCHEMBL1696749 | 0.74 | TDP1 (0.54) | MAPTRAB9ANPC1CA12CA1 | |
| SCHEMBL3661166 | 0.73 | RAB9A (0.49) | MAPTRAB9ANPC1CA12CA1 | |
| SCHEMBL11767203 | 0.72 | NPC1 (0.41) | MAPTRAB9ANPC1CA12CA1 | |
| SCHEMBL22460012 | 0.72 | MAPT (0.41) | MAPTRAB9ANPC1MAOAPOLB | |
| SCHEMBL3080728 | 0.72 | MAPT (0.75) | MAPTRAB9ANPC1ACHECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103869623-B | Coating composition | 默克专利有限公司 | 2017-07-21 | — | — | CN | disclosed |