Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | GLB1 | P16278 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | IDE | P14735 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698545 | 0.82 | RAB9A (0.50) | NPC1MAPTRAB9ALMNAHPGD | |
| SCHEMBL5698975 | 0.77 | NPC1 (0.46) | NPC1MAPTRAB9ALMNAHPGD | |
| SCHEMBL28167692 | 0.73 | THRB (0.38) | NPC1MAPTRAB9ALMNAHPGD | |
| SCHEMBL218279 | 0.70 | CES2 (0.37) | NPC1MAPTRAB9ALMNAHPGD | |
| SCHEMBL14841988 | 0.68 | MAPT (0.51) | NPC1MAPTRAB9ALMNAHPGD | |
| SCHEMBL11767203 | 0.67 | NPC1 (0.41) | NPC1MAPTRAB9ALMNAHPGD | |
| SCHEMBL8437177 | 0.66 | ALDH1A1 (0.47) | NPC1MAPTRAB9ALMNAHPGD | |
| SCHEMBL8437175 | 0.66 | ALDH1A1 (0.47) | NPC1MAPTRAB9ALMNAHPGD | |
| SCHEMBL2479589 | 0.66 | CYP1A2 (0.58) | NPC1MAPTRAB9ALMNAHPGD | |
| SCHEMBL2479591 | 0.66 | CYP1A2 (0.58) | NPC1MAPTRAB9ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845415-B1 | Process for producing an image using a first minimum bottom antireflective coating composition | AZ ELECTRONIC MATERIALS USA (US) | 2014-04-30 | — | — | EP | claimed |
| EP-1465877-B1 | POSITIVE-WORKING PHOTOIMAGEABLE BOTTOM ANTIREFLECTIVE COATING | AZ ELECTRONIC MATERIALS USA (US) | 2008-09-24 | — | — | EP | claimed |