Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28168054 | 0.80 | BCHE (0.52) | ACHEBCHEMEN1KMT2AAOC3 | |
| SCHEMBL15094004 | 0.79 | APLNR (0.59) | APLNRALDH1A1HTTSMN1; SMN2ACHE | |
| SCHEMBL14393820 | 0.77 | APLNR (0.56) | APLNRALDH1A1HTTSMN1; SMN2ACHE | |
| SCHEMBL385286 | 0.74 | HRH3 (0.58) | APLNRALDH1A1HTTSMN1; SMN2ACHE | |
| SCHEMBL4611890 | 0.74 | PYCR1 (0.69) | APLNRALDH1A1HTTSMN1; SMN2ACHE | |
| SCHEMBL17099352 | 0.72 | APLNR (0.55) | APLNRALDH1A1HTTSMN1; SMN2ACHE | |
| SCHEMBL12049800 | 0.72 | APLNR (0.59) | APLNRALDH1A1HTTSMN1; SMN2ACHE | |
| SCHEMBL5270803 | 0.72 | APLNR (0.59) | APLNRALDH1A1HTTSMN1; SMN2ACHE | |
| SCHEMBL10049173 | 0.71 | AOC3 (0.66) | APLNRALDH1A1HTTSMN1; SMN2PYCR1 | |
| SCHEMBL28074567 | 0.71 | IDO1 (0.56) | APLNRALDH1A1HTTSMN1; SMN2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107056799-B | The double heptene sulfamide compounds of suberic acid monoanilide group oxygen bridge, its synthetic method, application and anti-breast cancer medicines composition | 武汉宏兹生物技术有限公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-107056799-A | The double heptene sulfamide compounds of suberic acid monoanilide group oxygen bridge, its synthetic method, using and anti-breast cancer medicines composition | 武汉宏兹生物技术有限公司 | 2017-08-18 | — | — | CN | disclosed |