Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14393820 | 0.82 | APLNR (0.56) | APLNRALDH1A1HTTSMN1; SMN2PYCR1 | |
| SCHEMBL28168017 | 0.79 | APLNR (0.50) | APLNRALDH1A1HTTSMN1; SMN2PYCR1 | |
| SCHEMBL4611890 | 0.79 | PYCR1 (0.69) | APLNRALDH1A1HTTSMN1; SMN2PYCR1 | |
| SCHEMBL385286 | 0.79 | HRH3 (0.58) | APLNRALDH1A1HTTSMN1; SMN2PYCR1 | |
| SCHEMBL17099352 | 0.77 | APLNR (0.55) | APLNRALDH1A1HTTSMN1; SMN2PYCR1 | |
| SCHEMBL25546166 | 0.77 | PYCR1 (0.47) | PYCR1IDO1TAS2R14 | |
| SCHEMBL5270803 | 0.76 | APLNR (0.59) | APLNRALDH1A1HTTSMN1; SMN2PYCR1 | |
| SCHEMBL12049800 | 0.76 | APLNR (0.59) | APLNRALDH1A1HTTSMN1; SMN2PYCR1 | |
| SCHEMBL10049173 | 0.75 | AOC3 (0.66) | APLNRALDH1A1HTTSMN1; SMN2PYCR1 | |
| SCHEMBL28074567 | 0.75 | IDO1 (0.56) | APLNRALDH1A1HTTSMN1; SMN2PYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10618892-B2 | Processes for the preparation of a BACE inhibitor | MERCK SHARP & DOHME CORP. (US) | 2020-04-14 | — | — | US | disclosed |
| US-20150291514-A1 | N-Aminosulfonyl Benzamides | PFIZER LIMTED (GB) | 2015-10-15 | — | — | US | disclosed |
| EP-2800740-A1 | N-AMINOSULFONYL BENZAMIDES | Pfizer Limited (GB) | 2014-11-12 | — | — | EP | disclosed |
| WO-2013102826-A1 | N-AMINOSULFONYL BENZAMIDES | PFIZER LIMITED (GB) | 2013-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10618892-B2 | Processes for the preparation of a BACE inhibitor | BACE2, BACE1, APP | APLNR 4103/4885ALDH1A1 837/4885HTT 376/4885 |
| US-20150291514-A1 | N-Aminosulfonyl Benzamides | SCN7A, SCN2B, SCN1B | APLNR 2306/4885ALDH1A1 1823/4885HTT 3028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.