Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18307352 | 0.90 | NPSR1 (0.40) | NPSR1ALDH1A1MAPTHPGDPDE2A | |
| SCHEMBL30262303 | 0.90 | NPSR1 (0.40) | NPSR1ALDH1A1MAPTHPGDPDE2A | |
| SCHEMBL23170322 | 0.89 | NPSR1 (0.40) | NPSR1ALDH1A1MAPTHPGDPDE2A | |
| SCHEMBL28169333 | 0.89 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDGAAATM | |
| SCHEMBL28169284 | 0.87 | NPSR1 (0.40) | NPSR1ALDH1A1MAPTHPGDPDE2A | |
| SCHEMBL28899732 | 0.83 | CES2 (0.41) | ALDH1A1MAPTHPGDPDE2AKDM4E | |
| SCHEMBL22647486 | 0.82 | MAPT (0.39) | NPSR1ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL22620690 | 0.82 | MAPT (0.39) | NPSR1ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL22620678 | 0.81 | LMNA (0.39) | NPSR1ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL22621695 | 0.79 | MAPT (0.36) | NPSR1ALDH1A1MAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098846-B | N-acyl sulfonamide FBPase inhibitor, preparation method thereof, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2020-10-09 | — | — | CN | disclosed |
| CN-107098846-A | N- acyl sulfonamides class FBPase inhibitor, its preparation method, pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2017-08-29 | — | — | CN | disclosed |