Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAB2 | O43741 | 17/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 17/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 17/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 17/20 | 0.48 |
| ▸ | PRKAG3 | Q9UGI9 | 17/20 | 0.48 |
| ▸ | PRKAG2 | Q9UGJ0 | 17/20 | 0.48 |
| ▸ | PRKAB1 | Q9Y478 | 17/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23612266 | 0.82 | PRKAG1 (0.66) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL27723109 | 0.80 | F7 (0.71) | F7F3NR4A2 | |
| SCHEMBL28770407 | 0.80 | NR4A2 (0.61) | F7F3NR4A2 | |
| SCHEMBL28170057 | 0.79 | GPR84 (0.49) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL27545498 | 0.79 | NR4A2 (0.40) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL23612197 | 0.76 | PRKAB2 (0.48) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL29988111 | 0.76 | PRKAB2 (0.48) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL27640249 | 0.76 | PRKAB2 (0.42) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL613338 | 0.75 | MAPK1 (0.57) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL28940822 | 0.73 | HPGD (0.49) | F7F3NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428691-A | Bicyclic formamides of 2 aryl quinoline 4 of substituted N and application thereof | 拜耳制药股份公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-107074773-A | Substituted N, the formamide of 2 biaryl quinolin 4 and application thereof | 拜耳制药股份公司 | 2017-08-18 | — | — | CN | disclosed |