SCHEMBL28172192

SCHEMBL28172192

CCCCCCCCCCCCCCCCCC(=O)C1([SiH2]C)CCCCO1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 4/20 0.37
ACP1 P24666 1/20 0.37
CDC25B P30305 1/20 0.37
CES2 O00748 3/20 0.35
CES1 P23141 3/20 0.35
GPR84 Q9NQS5 7/20 0.34
PPARG P37231 7/20 0.34
PPARD Q03181 7/20 0.34
PPARA Q07869 7/20 0.34
HDAC11 Q96DB2 5/20 0.34
TSHR P16473 4/20 0.34
ALDH1A1 P00352 2/20 0.34
TLR2 O60603 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
FABP4 P15090 2/20 0.34
SLC22A6 Q4U2R8 1/20 0.34
SLC22A8 Q8TCC7 1/20 0.34
MEN1 O00255 1/20 0.34
ESR1 P03372 1/20 0.34
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27839524 1.00 PTPN1 (0.37) PTPN1ACP1CDC25BCES2CES1
SCHEMBL28923218 0.81 PTPN1 (0.33) PTPN1ACP1CDC25BCES2CES1
SCHEMBL29013293 0.76 PTPN1 (0.38) PTPN1ACP1CDC25BCES2CES1
SCHEMBL28118582 0.73
SCHEMBL28150990 0.73 NAAA (0.39) NAAA
SCHEMBL28118207 0.73 NAAA (0.39) NAAA
SCHEMBL7233038 0.70 CES2 (0.48) PTPN1CES2CES1GPR84PPARG
SCHEMBL27925015 0.70
SCHEMBL25434480 0.69 CES1 (0.34) PTPN1ACP1CDC25BCES2CES1
SCHEMBL29037211 0.68 KMT2A (0.39) PTPN1ACP1CDC25BCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107106549-A γ-diketone for treating and preventing aging skin and wrinkle 萨穆梅德有限公司 2017-08-29 CN disclosed