Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2820806 | 0.82 | PARP1 (0.56) | PARP1BRD4 | |
| SCHEMBL7032508 | 0.79 | PARP1 (0.52) | PARP1 | |
| SCHEMBL2817264 | 0.79 | PARP1 (0.34) | PARP1ALDH1A1LMNATSHRPAX8 | |
| SCHEMBL2497545 | 0.75 | PARP1 (0.50) | PARP1BRD4 | |
| SCHEMBL7856459 | 0.73 | PARP1 (0.47) | PARP1ALDH1A1PKMLMNAKDM4E | |
| SCHEMBL2611049 | 0.73 | PARP1 (0.46) | PARP1ALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL2128641 | 0.72 | ALDH1A1 (0.40) | PARP1ALDH1A1PKMBRD4 | |
| SCHEMBL24351926 | 0.70 | PARP1 (0.44) | PARP1ALDH1A1LMNASMN1; SMN2BRD4 | |
| SCHEMBL630485 | 0.70 | PARP1 (1.00) | PARP1 | |
| SCHEMBL2127994 | 0.70 | HTR2A (0.47) | PARP1LMNABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010110686-A1 | PYRIMIDINYL AND 1,3,5 TRIAZINYL BENZIMIDAZOLES AND THEIR USE IN CANCER THERAPY | PATHWAY THERAPEUTICS LIMITED (NZ) | 2010-09-30 | — | — | WO | disclosed |