Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2820806 | 0.81 | PARP1 (0.56) | PARP1 | |
| SCHEMBL2817256 | 0.79 | PARP1 (0.54) | PARP1 | |
| SCHEMBL7036443 | 0.78 | PARP1 (0.34) | PARP1 | |
| SCHEMBL20032408 | 0.77 | PARP1 (0.42) | PARP1 | |
| SCHEMBL18713659 | 0.76 | TSHR (0.42) | PARP1 | |
| SCHEMBL2497545 | 0.74 | PARP1 (0.50) | PARP1PRMT5 | |
| SCHEMBL7856459 | 0.72 | PARP1 (0.47) | PARP1PRMT5 | |
| SCHEMBL2611049 | 0.72 | PARP1 (0.46) | PARP1 | |
| SCHEMBL2127994 | 0.72 | HTR2A (0.47) | PARP1 | |
| SCHEMBL1972827 | 0.70 | GPR84 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6756384-B2 | TREATMENT OF DISEASES AND DISORDERS RELATED TO THE HISTAMINE H3 RECEPTOR. | NOVO NORDISK A/S (DK) | 2004-06-29 | — | — | US | disclosed |
| US-6437147-B1 | FOR THERAPY OF DISEASES OF CENTRAL NERVOUS SYSTEM, PERIPHERAL NERVOUS SYSTEM, CARDIOVASCULAR SYSTEM, PULMONARY SYSTEM, GASTROINTESTINAL SYSTEM AND ENDOCRINOLOGICAL SYSTEM | NOVO NORDISK (DK) | 2002-08-20 | — | — | US | disclosed |