Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28187328 | 0.80 | FDPS (0.41) | FDPSHDAC1HDAC6CYP1A2ALDH1A1 | |
| SCHEMBL20979882 | 0.73 | HDAC1 (0.43) | FDPSHDAC1HDAC6CYP1A2ALDH1A1 | |
| SCHEMBL20979880 | 0.71 | HDAC1 (0.42) | FDPSHDAC1HDAC6CYP1A2ALDH1A1 | |
| SCHEMBL3421967 | 0.70 | FDPS (0.46) | FDPSHDAC1HDAC6CYP1A2ALDH1A1 | |
| SCHEMBL27337608 | 0.70 | HDAC1 (0.42) | FDPSHDAC1HDAC6CYP1A2ALDH1A1 | |
| SCHEMBL8542831 | 0.70 | LTA4H (0.39) | FDPSHDAC1HDAC6CYP1A2ALDH1A1 | |
| SCHEMBL10774226 | 0.68 | FDPS (0.41) | FDPSHDAC1HDAC6CYP1A2ALDH1A1 | |
| SCHEMBL1692456 | 0.68 | FDPS (0.56) | FDPSHDAC1HDAC6CYP1A2ALDH1A1 | |
| SCHEMBL2126857 | 0.68 | HDAC1 (0.49) | FDPSHDAC1HDAC6CYP1A2ALDH1A1 | |
| SCHEMBL5828209 | 0.67 | FDPS (0.40) | FDPSHDAC1HDAC6CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107184582-A | It is a kind of to be used to treat composition of motor neuron disease and application thereof | 岳茂兴 | 2017-09-22 | — | — | CN | disclosed |
| CN-107115332-A | It is a kind of to be used to treat composition of motor neuron disease and application thereof | 岳茂兴 | 2017-09-01 | — | — | CN | disclosed |