Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875070 | 0.86 | CYP46A1 (0.39) | CYP46A1MAPK14CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL28172765 | 0.85 | IDO1 (0.51) | CYP46A1MAPK14CASP6ALDH1A1CYP2D6 | |
| SCHEMBL24312483 | 0.79 | CYP2D6 (0.43) | CYP46A1CASP6ALDH1A1CYP2D6HSD17B10 | |
| SCHEMBL7503631 | 0.79 | CASP6 (0.42) | CYP46A1MAPK14CASP6CYP2D6MAPK13 | |
| SCHEMBL24312484 | 0.79 | DPP4 (0.46) | CYP46A1MAPK14CASP6CYP2D6MAPK13 | |
| SCHEMBL28144739 | 0.79 | CASP6 (0.39) | CYP46A1MAPK14CASP6ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL29473296 | 0.78 | DPP4 (0.44) | CYP46A1MAPK14CASP6CYP2D6MAPK13 | |
| SCHEMBL10601314 | 0.78 | MAPK9 (0.43) | CYP46A1MAPK14CASP6CYP2D6MAPK13 | |
| Hydrochloric Acid SCHEMBL23498194 | 0.75 | TAAR1 (0.39) | CASP6HTR2A | |
| Hydrochloric Acid SCHEMBL29723641 | 0.75 | TAAR1 (0.39) | CASP6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107141295-A | A kind of simple synthesis of uracil derivative | 重庆文理学院 | 2017-09-08 | — | — | CN | disclosed |