Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28172764 | 0.85 | CYP46A1 (0.43) | TSHRALDH1A1CYP46A1FAAHCYP2D6 | |
| SCHEMBL4727994 | 0.81 | L3MBTL1 (0.65) | IDO1IDO2ABCB1TSHRHTT | |
| Hydrochloric Acid SCHEMBL23498194 | 0.81 | TAAR1 (0.39) | CASP6 | |
| Hydrochloric Acid SCHEMBL29723641 | 0.81 | TAAR1 (0.39) | CASP6 | |
| SCHEMBL27897863 | 0.79 | CYP2D6 (0.48) | ALOX15ALDH1A1MAPTCYP46A1CYP1A2 | |
| SCHEMBL24312483 | 0.78 | CYP2D6 (0.43) | ALOX15ALDH1A1MAPTCYP46A1CYP1A2 | |
| SCHEMBL7503631 | 0.78 | CASP6 (0.42) | CYP46A1CYP1A2CYP3A4CYP2D6MAPK14 | |
| SCHEMBL24312484 | 0.78 | DPP4 (0.46) | CYP46A1CYP1A2CYP2D6MAPK14CASP6 | |
| SCHEMBL28144739 | 0.78 | CASP6 (0.39) | TSHRALOX15ALDH1A1MAPTCYP46A1 | |
| Hydrochloric Acid SCHEMBL29473296 | 0.77 | DPP4 (0.44) | CYP46A1CYP1A2CYP2D6MAPK14CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107141295-A | A kind of simple synthesis of uracil derivative | 重庆文理学院 | 2017-09-08 | — | — | CN | disclosed |