Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.58 |
| ▸ | HAT1 | O14929 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21274635 | 0.82 | HCAR3 (0.54) | HCAR3HAT1EP300KDM4EALDH1A1 | |
| SCHEMBL1569893 | 0.79 | HCAR3 (0.60) | HCAR3HAT1EP300KDM4EALDH1A1 | |
| SCHEMBL12953802 | 0.79 | HCAR3 (0.56) | HCAR3HAT1EP300KDM4EALDH1A1 | |
| SCHEMBL1569897 | 0.79 | HCAR3 (0.60) | HCAR3HAT1EP300KDM4EALDH1A1 | |
| SCHEMBL12953967 | 0.78 | HCAR3 (0.76) | HCAR3KDM4EALDH1A1AURKARPS6KB1 | |
| SCHEMBL14416656 | 0.77 | HCAR3 (0.57) | HCAR3HAT1EP300KDM4EALDH1A1 | |
| SCHEMBL27961404 | 0.75 | HCAR3 (0.60) | HCAR3HAT1EP300KDM4EALDH1A1 | |
| SCHEMBL13304709 | 0.75 | HCAR3 (0.55) | HCAR3HAT1EP300KDM4EALDH1A1 | |
| SCHEMBL28782092 | 0.75 | HCAR3 (0.81) | HCAR3KDM4EALDH1A1HDAC1AURKA | |
| SCHEMBL28173150 | 0.74 | HCAR3 (0.58) | HCAR3HAT1EP300KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108593-A | Substituted oxazole and thiazole-based carboxamide and urea derivatives as vanilloid receptor ligands II | 美迪福伦DBT有限公司 | 2017-08-29 | — | — | CN | disclosed |