Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28007096 | 0.82 | EGFR (0.46) | IDO1AREGFRTDP1LTA4H | |
| SCHEMBL2130108 | 0.81 | IDO1 (0.44) | IDO1ARLTA4HKDM4EALDH1A1 | |
| SCHEMBL15637274 | 0.80 | AR (0.46) | IDO1ARLTA4HRBP4MAOB | |
| SCHEMBL28250930 | 0.78 | LOXL2 (0.50) | IDO1AREGFRTDP1LTA4H | |
| SCHEMBL13726969 | 0.76 | MAOB (0.46) | IDO1ARLTA4HRBP4MAOB | |
| SCHEMBL13728273 | 0.75 | IDO1 (0.42) | IDO1AREGFRLTA4HMAOB | |
| SCHEMBL9485705 | 0.74 | NPC1 (0.49) | IDO1ARTAAR1KDM4EALDH1A1 | |
| SCHEMBL5380250 | 0.74 | KDM4E (0.56) | IDO1ARTDP1LTA4HMAOB | |
| SCHEMBL5206144 | 0.73 | IDO1 (0.55) | IDO1ARTDP1LTA4HMAOB | |
| SCHEMBL17329111 | 0.72 | IDO1 (0.59) | IDO1TDP1MAOBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104395324-B | Mi Zuo Bing oxadiazoles and imidazo thiadiazoles derivative | 阿瑞斯贸易股份有限公司 | 2017-09-12 | — | — | CN | disclosed |