SCHEMBL9485705

SCHEMBL9485705

Fc1ccccc1Cc1ncccn1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
ALDH1A1 P00352 3/20 0.49
HTT P42858 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
HTR2C P28335 1/20 0.45
HTR2B P41595 1/20 0.45
LMNA P02545 1/20 0.45
GAA P10253 1/20 0.45
TAAR1 Q96RJ0 2/20 0.45
POLB P06746 1/20 0.45
KDM4E B2RXH2 3/20 0.42
ADORA2A P29274 1/20 0.42
ADORA2B P29275 1/20 0.42
ADORA1 P30542 1/20 0.42
IDO1 P14902 2/20 0.42
AR P10275 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
PKM P14618 1/20 0.41
HTR6 P50406 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9953712 0.79 L3MBTL1 (0.50) NPC1RAB9AALDH1A1HTTL3MBTL1
SCHEMBL3301625 0.78 TAAR1 (0.59) ALDH1A1L3MBTL1LMNATAAR1KDM4E
SCHEMBL28428643 0.76 ALDH1A1 (0.55) NPC1RAB9AALDH1A1HTTL3MBTL1
SCHEMBL27794864 0.75 VNN1 (0.50) ALDH1A1HTR2CHTR2BKDM4EHPGD
SCHEMBL21087072 0.74 HTR2C (0.45) NPC1RAB9AALDH1A1HTR2CHTR2B
SCHEMBL8745956 0.74 HSPA5 (0.62) ALDH1A1L3MBTL1TAAR1KDM4EADORA2A
SCHEMBL28174656 0.74 IDO1 (0.47) ALDH1A1TAAR1KDM4EIDO1AR
SCHEMBL7407579 0.72 CYP17A1 (0.46) NPC1RAB9AALDH1A1HTTL3MBTL1
SCHEMBL2437697 0.72 HTR6 (0.43) NPC1RAB9AALDH1A1HTTHTR2C
Hydrochloric Acid SCHEMBL27858482 0.72 TAAR1 (0.52) ALDH1A1L3MBTL1LMNATAAR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118354672-A Fungicidal compositions 先正达农作物保护股份公司 2024-07-16 CN disclosed
CN-118234723-A Pesticidally active heterocyclic derivatives with sulfoximine containing substituents 先正达农作物保护股份公司 2024-06-21 CN disclosed
CN-117279895-A (hetero) arylamide compound and pest control agent 日本曹达株式会社 2023-12-22 CN disclosed
CN-116801721-A Weed control method 组合化学工业株式会社 2023-09-22 CN disclosed
CN-116783193-A Pesticidally active heterocyclic derivatives with sulfur containing substituents 先正达农作物保护股份公司 2023-09-19 CN disclosed
CN-110546152-B Bicyclic pesticide compounds 巴斯夫欧洲公司 2023-09-08 CN disclosed
EP-0290558-B1 ANTIFOLATE AGENTS BTG INTERNATIONAL LIMITED (GB) 1993-06-16 EP disclosed
US-4992444-A Antitumor agents, skin disorders BRITISH TECHNOLOGY GROUP LIMITED (GB) 1991-02-12 US disclosed
EP-0290558-A1 ANTIFOLATE AGENTS. STEVENS MALCOLM FRANCIS GRAHAM (GB) 1988-11-17 EP disclosed
WO-1988004293-A1 ANTIFOLATE AGENTS STEVENS MALCOLM FRANCIS GRAHAM (GB) 1988-06-16 WO disclosed