SCHEMBL28174678

SCHEMBL28174678

NC(=Cc1ccccc1)c1cccc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.46
HNF4A P41235 1/20 0.43
PLAU P00749 1/20 0.36
PLAT P00750 1/20 0.36
GRIN2D O15399 2/20 0.36
GRIN3B O60391 2/20 0.36
GRIN1 Q05586 2/20 0.36
GRIN2A Q12879 2/20 0.36
GRIN2B Q13224 2/20 0.36
GRIN2C Q14957 2/20 0.36
GRIN3A Q8TCU5 2/20 0.36
PARP1 P09874 1/20 0.35
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 2/20 0.35
HPGD P15428 1/20 0.35
BCL2L1 Q07817 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196210 0.87 BCAT2 (0.55) BCAT2HNF4AGRIN2DGRIN3BGRIN1
SCHEMBL5010723 0.79 HNF4A (0.53) BCAT2HNF4AALDH1A1HSD17B10HPGD
SCHEMBL18543084 0.79 MCL1 (0.44) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL3868848 0.79 MCL1 (0.44) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL27484720 0.77 ESR1 (0.41) BCAT2HNF4APLAUPLATALDH1A1
SCHEMBL28613771 0.77 BCAT2 (0.50) BCAT2HNF4APLAUPLATPARP1
SCHEMBL6832583 0.77 BCAT2 (0.50) BCAT2HNF4APLAUPLATALDH1A1
SCHEMBL2025737 0.77 BCAT2 (0.71) BCAT2HNF4APLAUPLATPARP1
Hydrochloric Acid SCHEMBL27966297 0.75 BCAT2 (0.69) BCAT2HNF4APLAUPLATPARP1
SCHEMBL5008857 0.74 HNF4A (0.48) BCAT2HNF4APLAUPLATALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104335382-B Substrate for organic electronic device 株式会社LG化学 2017-09-12 CN disclosed