SCHEMBL5010723

SCHEMBL5010723

c1ccc(-c2cccc([C](c3cccc(-c4ccccc4)c3-c3ccccc3)c3cccc(-c4ccccc4)c3-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.53
BCAT2 O15382 1/20 0.47
ALDH1A1 P00352 5/20 0.44
HSD17B10 Q99714 2/20 0.44
HPGD P15428 1/20 0.44
BCL2L1 Q07817 1/20 0.44
HDAC4 P56524 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CHRNB2 P17787 4/20 0.41
CHRNB4 P30926 4/20 0.41
CHRNA3 P32297 4/20 0.41
CHRNA4 P43681 4/20 0.41
BACE1 P56817 1/20 0.41
FABP3 P05413 1/20 0.40
FABP4 P15090 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5010686 0.90 HNF4A (0.48) HNF4ABCAT2ALDH1A1HSD17B10HPGD
SCHEMBL5008857 0.90 HNF4A (0.48) HNF4ABCAT2ALDH1A1HSD17B10HPGD
SCHEMBL5010021 0.87 MAPT (0.49) HNF4ABCAT2ALDH1A1HSD17B10HPGD
SCHEMBL5010126 0.83 HNF4A (0.50) HNF4ABCAT2ALDH1A1HSD17B10HPGD
SCHEMBL8778491 0.83 HNF4A (0.60) HNF4ABCAT2ALDH1A1HDAC4HDAC2
SCHEMBL225203 0.83 HNF4A (0.71) HNF4ABCAT2ALDH1A1HSD17B10HPGD
SCHEMBL2843780 0.80 BCAT2 (0.60) HNF4ABCAT2ALDH1A1HSD17B10HPGD
SCHEMBL192418 0.80 ALDH1A1 (0.50) HNF4ABCAT2ALDH1A1HSD17B10HPGD
SCHEMBL7573634 0.79 HNF4A (0.47) HNF4ABCAT2ALDH1A1HSD17B10HPGD
SCHEMBL28380645 0.79 HNF4A (0.56) HNF4ABCAT2ALDH1A1HDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207864-A1 Organosilanes, Process For Production of the Same, and Use Thereof SHARP KABUSHIKI KAISHA (JP) 2008-08-28 US disclosed