Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955782 | 0.81 | NAPRT (0.53) | ALDH1A1KDM4EKMT2AMEN1KDM6B | |
| SCHEMBL21355935 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4EKMT2AMAPTGLA | |
| SCHEMBL25863829 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1KDM4ETDP1KDM5B | |
| SCHEMBL277947 | 0.77 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL25863831 | 0.77 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL25863834 | 0.72 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL1322157 | 0.71 | NAPRT (0.68) | SMN1; SMN2ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL29489950 | 0.71 | NAPRT (0.68) | SMN1; SMN2ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL30898769 | 0.71 | NOS3 (0.48) | SMN1; SMN2ALDH1A1KDM4CNAPRTPRKCI | |
| SCHEMBL13911137 | 0.71 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074805-A | GLS1 inhibitor for treating disease | 德州大学系统董事会 | 2017-08-18 | — | — | CN | disclosed |